The Illusion of Evidence-Based Medicine: Exposing the crisis of credibility in clinical research

by Jon Jureidini, PhD & Leemon B. McHenry, PhD

An exposé of the corruption of medicine by the pharmaceutical industry at every level, from exploiting the vulnerable destitute for drug testing, through manipulation of research data, to disease mongering and promoting drugs that do more harm than good.

Authors, Professor Jon Jureidini and Dr Leemon McHenry, made critical contributions to exposing the scientific misconduct in two infamous trials of antidepressants. Ghostwritten publications of these trials were highly influential in prescriptions of paroxetine (Paxil) and citalopram (Celexa) in paediatric and adolescent depression, yet both trials (Glaxo Smith Kline’s paroxetine study 329 and Forest Laboratories’ citalopram study CIT-MD-18) seriously misrepresented the efficacy and safety data.

The Illusion of Evidence-Based Medicine provides a detailed account of these studies and argues that medicine desperately needs to re-evaluate its relationship with the pharmaceutical industry.

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